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Doxazosin, as mesilate (Alfadil XL) can be taken with or without food.
Doxazosin, as mesilate (Alfadil XL) tablets should be swallowed whole with a sufficient amount of liquid. Patients should not chew, divide or crush the tablets (see Information for Patients under Precautions).
The optimal effect of doxazosin may take up to 4 weeks. If necessary, the dosage may be increased following this period to 8 mg once daily according to patient response.
The maximum recommended dose is 8 mg once daily.
Use in Elderly: Normal adult dosage is recommended.
Use in Renally Impaired Patients: Since the pharmacokinetics of doxazosin are unchanged in patients with renal insufficiency, and there is no evidence that doxazosin aggravates existing renal dysfunction, the usual dosages may be used in these patients.
Use in Hepatically Impaired Patients: See Precautions.
Use in Children: The safety and efficacy of doxazosin in children have not been established.
